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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Postseason Career Leaderboard |
|---|---|---|---|---|
| 1 | Fernando Valenzuela* | 13.24 | 1984 | |
| 2 | Christy Mathewson# | 13.22 | 1997 | |
| 3 | Happy Townsend# | 12.69 | 1984 | |
| 4 | Fernando Valenzuela* | 12.60 | 1983 | |
| 5 | Roger Clemens# | 12.53 | 1984 | |
| 6 | Bruce Berenyi | 11.53 | 1984 | |
| 7 | Marty Bystrom | 10.62 | 1984 | |
| 8 | Dave Stieb | 10.17 | 1984 | |
| 9 | Rick Rhoden | 10.04 | 1984 | |
| 10 | Hal Newhouser# | 10.00 | 1999 | |
| 11 | Willie Foster# | 9.91 | 1998 | |
| 12 | Jeff Weaver# | 9.53 | 1993 | |
| 13 | Van Mungo# | 9.20 | 1996 | |
| 14 | Patrick Corbin | 9.19 | 1984 | |
| 14 | Ernie Broglio# | 9.19 | 1995 | |
| 16 | Van Mungo# | 9.18 | 1994 | |
| 17 | John Tudor | 9.17 | 1984 | |
| 18 | Bill Wise# | 9.11 | 1992 | |
| 19 | Mark W Davis | 9.00 | 1986 | |
| 19 | Britt Burns | 9.00 | 1984 | |
| 19 | Don Robinson | 9.00 | 1984 | |
| 22 | Ron Guidry | 8.92 | 1984 | |
| 23 | Steve Carlton | 8.87 | 1983 | |
| 24 | Bert Inks# | 8.82 | 1997 | |
| 25 | John Candelaria | 8.80 | 1984 | |
| 26 | Bruce Berenyi | 8.79 | 1983 | |
| 27 | Scott Sanderson | 8.78 | 1980 | |
| 28 | Bob Ojeda | 8.61 | 1984 | |
| 29 | Bob Knepper | 8.39 | 1984 | |
| 30 | J R Richard | 8.38 | 1984 | |
| 30 | Al Mamaux# | 8.38 | 1999 | |
| 32 | Fernando Valenzuela* | 8.27 | 1982 | |
| 32 | Al Orth# | 8.27 | 1993 | |
| 34 | Jose DeLeon | 8.25 | 1984 | |
| 35 | Ed Brandt# | 8.24 | 1997 | |
| 36 | Yu Darvish# | 8.22 | 1998 | |
| 36 | Lefty Grove# | 8.22 | 1987 | |
| 38 | Jim Bunning# | 8.00 | 1998 | |
| 38 | Scott Sanderson | 8.00 | 1983 | |
| 40 | Camilo Pascual# | 7.97 | 1984 | |
| 41 | Mario Soto | 7.88 | 1982 | |
| 41 | Al Mamaux# | 7.88 | 1998 | |
| 43 | Roger Clemens# | 7.85 | 1993 | |
| 43 | Kevin Appier# | 7.85 | 1994 | |
| 45 | Mario Soto | 7.82 | 1981 | |
| 46 | Jack McDowell | 7.80 | 1986 | |
| 47 | Dave LaPoint | 7.76 | 1984 | |
| 48 | Bob Welch | 7.71 | 1987 | |
| 49 | Fernando Valenzuela* | 7.67 | 1986 | |
| 50 | Ben Sheets# | 7.66 | 1993 | |
| 50 | Mario Soto | 7.66 | 1983 | |
| 52 | Dave Righetti# | 7.64 | 1994 | |
| 52 | Early Wynn# | 7.64 | 1999 | |
| 54 | Paul Derringer# | 7.54 | 1999 | |
| 54 | Felix Hernandez# | 7.54 | 1997 | |
| 56 | Roger Clemens# | 7.31 | 1989 | |
| 56 | Al Orth# | 7.31 | 1998 | |
| 58 | Roger Clemens# | 7.29 | 1987 | |
| 59 | Nolan Ryan | 7.25 | 1983 | |
| 60 | Dan Haren# | 7.15 | 1993 | |
| 61 | Dan Haren# | 7.03 | 1994 | |
| 62 | Pascual Perez | 7.00 | 1988 | |
| 62 | Pete Vuckovich | 7.00 | 1981 | |
| 64 | Frank Tanana | 6.97 | 1985 | |
| 64 | Carlos Zambrano# | 6.97 | 1995 | |
| 66 | Mike Scott | 6.92 | 1987 | |
| 67 | Floyd Bannister | 6.88 | 1982 | |
| 68 | David Palmer | 6.87 | 1988 | |
| 69 | Scott Elarton# | 6.86 | 1998 | |
| 70 | Len Barker | 6.75 | 1982 | |
| 70 | Steve Carlton | 6.75 | 1980 | |
| 72 | Bill Wise# | 6.63 | 1990 | |
| 73 | Mike O'Neill# | 6.60 | 1999 | |
| 74 | John Denny | 6.46 | 1984 | |
| 75 | Patrick Corbin | 6.43 | 1988 | |
| 76 | Jack Fisher# | 6.41 | 1998 | |
| 77 | Jack Morris | 6.39 | 1987 | |
| 78 | Fernando Valenzuela* | 6.37 | 1988 | |
| 79 | Jim Abbott# | 6.35 | 1993 | |
| 79 | Roger Clemens# | 6.35 | 1982 | |
| 81 | Steve Carlton | 6.30 | 1982 | |
| 81 | Mario Soto | 6.30 | 1985 | |
| 83 | Kenta Maeda | 6.27 | 1989 | |
| 84 | Bruce Berenyi | 6.23 | 1981 | |
| 84 | Steve Carlton | 6.23 | 1981 | |
| 86 | Vinegar Bend Mizell# | 6.21 | 1992 | |
| 87 | Charlie Lea | 6.19 | 1984 | |
| 87 | Floyd Bannister | 6.19 | 1980 | |
| 89 | Lefty Grove# | 6.17 | 1989 | |
| 90 | Vinegar Bend Mizell# | 6.10 | 1990 | |
| 91 | Tommy Bond# | 6.08 | 1997 | |
| 92 | Lefty Grove# | 6.04 | 1998 | |
| 93 | Jordan M Zimmermann# | 6.00 | 1997 | |
| 94 | Bob Bruce | 5.94 | 1993 | |
| 94 | Floyd Bannister | 5.94 | 1983 | |
| 96 | Johnny Cueto# | 5.91 | 1998 | |
| 97 | Jim Bunning# | 5.89 | 1999 | |
| 98 | Jesse Barnes# | 5.88 | 1998 | |
| 99 | Frank Tanana | 5.87 | 1980 | |
| 100 | Roger Clemens# | 5.86 | 1986 |
