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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Bryce Harper# | 429 | 1981-1999 | |
| 2 | Harmon Killebrew# | 374 | 1954-1999 | |
| 3 | Hal Trosky Sr# | 366 | 1991-1999 | |
| 4 | Miguel Cabrera# | 334 | 1988-1999 | |
| 5 | Eddie Murray* | 319 | 1980-1995 | |
| 6 | Wally Berger# | 294 | 1992-1999 | |
| 6 | Andre Dawson | 294 | 1980-1995 | |
| 8 | Adam Dunn# | 286 | 1991-1999 | |
| 9 | Ellis Burks# | 274 | 1985-1999 | |
| 10 | Harold Baines | 268 | 1981-1998 | |
| 10 | George C Scott# | 268 | 1989-1999 | |
| 12 | Rickey Henderson* | 263 | 1980-1997 | |
| 13 | Dave Henderson | 256 | 1982-1996 | |
| 14 | Yordan Alvarez# | 255 | 1987-1999 | |
| 15 | Dave Winfield | 244 | 1980-1993 | |
| 16 | Edgardo Alfonzo# | 231 | 1986-1998 | |
| 16 | Max Muncy | 231 | 1983-1994 | |
| 18 | Mark Reynolds# | 229 | 1985-1999 | |
| 19 | Jack Clark | 228 | 1980-1992 | |
| 20 | Dale Murphy | 225 | 1980-1992 | |
| 21 | Dwight Evans | 223 | 1980-1993 | |
| 22 | Jorge Posada# | 218 | 1986-1999 | |
| 23 | Robin Yount* | 214 | 1980-1995 | |
| 24 | Mike Schmidt | 213 | 1980-1989 | |
| 25 | Trevor Story# | 212 | 1992-1999 | |
| 26 | Alan Trammell* | 203 | 1980-1994 | |
| 27 | Harry Steinfeldt# | 201 | 1988-1999 | |
| 28 | Tony Clark# | 199 | 1993-1999 | |
| 29 | Rob Deer# | 196 | 1990-1999 | |
| 29 | Jim Rice | 196 | 1980-1990 | |
| 29 | Tim Wallach | 196 | 1980-1999 | |
| 32 | Jose Altuve# | 194 | 1988-1999 | |
| 32 | George Brett* | 194 | 1980-1991 | |
| 34 | Mike Tiernan# | 191 | 1987-1999 | |
| 35 | Elmer Flick# | 189 | 1992-1999 | |
| 36 | Travis Hafner | 188 | 1984-1999 | |
| 37 | Chet Lemon | 187 | 1980-1991 | |
| 38 | Jimmy Rollins# | 185 | 1988-1999 | |
| 39 | Jerry Lynch# | 182 | 1987-1999 | |
| 40 | J T Snow# | 181 | 1992-1999 | |
| 41 | Lou Whitaker | 180 | 1980-1996 | |
| 42 | Brian Downing | 179 | 1980-1994 | |
| 43 | Michael Brantley# | 177 | 1987-1999 | |
| 43 | Chris B Young# | 177 | 1991-1999 | |
| 45 | David Wright# | 176 | 1994-1999 | |
| 46 | Kirk Gibson | 175 | 1981-1993 | |
| 47 | Von Hayes# | 173 | 1991-1999 | |
| 48 | Woodie Held# | 167 | 1992-1999 | |
| 49 | Pedro Guerrero | 164 | 1980-1992 | |
| 49 | Jimmy T Williams# | 164 | 1991-1999 | |
| 51 | Matt Nokes# | 162 | 1991-1999 | |
| 52 | Mike D Young | 160 | 1988-1996 | |
| 53 | Sean Rodriguez# | 158 | 1988-1999 | |
| 54 | Cito Gaston# | 156 | 1990-1999 | |
| 54 | Bob Horner | 156 | 1980-1988 | |
| 54 | Brook Jacoby# | 156 | 1990-1998 | |
| 57 | Mickey Mantle# | 153 | 1951-1999 | |
| 58 | Doug DeCinces | 152 | 1980-1988 | |
| 58 | Tim Raines Sr* | 152 | 1981-1996 | |
| 60 | Bill Freehan# | 150 | 1989-1999 | |
| 60 | Terry Steinbach# | 150 | 1991-1999 | |
| 62 | Al Dark# | 149 | 1987-1999 | |
| 62 | Fred Lynn | 149 | 1980-1991 | |
| 62 | Alexis Rios# | 149 | 1990-1999 | |
| 65 | Brandon Nimmo# | 148 | 1991-1999 | |
| 66 | Johnny Frederick | 146 | 1987-1997 | |
| 66 | Paul Molitor | 146 | 1980-1996 | |
| 68 | Tom Haller# | 145 | 1990-1999 | |
| 68 | Gary Roenicke | 145 | 1980-1989 | |
| 70 | Jim Wynn# | 144 | 1994-1999 | |
| 71 | Kris Bryant# | 143 | 1993-1999 | |
| 72 | Joe Oliver# | 142 | 1988-1999 | |
| 72 | Larry Parrish | 142 | 1980-1990 | |
| 74 | Gary Carter | 139 | 1980-1991 | |
| 75 | Justin Upton# | 138 | 1992-1999 | |
| 76 | Lloyd Moseby | 135 | 1982-1995 | |
| 76 | Dan Thomas# | 135 | 1989-1997 | |
| 78 | Rio Ruiz# | 133 | 1990-1998 | |
| 79 | Jeff Blauser# | 131 | 1984-1998 | |
| 80 | Randy Velarde# | 130 | 1986-1999 | |
| 81 | Joe Birmingham# | 129 | 1989-1999 | |
| 81 | Bobby Veach# | 129 | 1994-1999 | |
| 83 | Orlando Merced# | 126 | 1991-1999 | |
| 83 | Anthony Rizzo# | 126 | 1994-1999 | |
| 85 | Eddie Yost | 125 | 1944-1992 | |
| 86 | Charles Johnson | 124 | 1986-1997 | |
| 87 | Jim Fregosi# | 121 | 1991-1999 | |
| 88 | Cecil Cooper | 120 | 1980-1987 | |
| 88 | Gorman Thomas | 120 | 1980-1989 | |
| 90 | Chuck Knoblauch# | 118 | 1987-1999 | |
| 91 | Don Lock# | 117 | 1993-1999 | |
| 92 | Hank Blalock# | 115 | 1994-1999 | |
| 93 | John Carney | 114 | 1987-1998 | |
| 93 | Oscar Gamble | 114 | 1980-1984 | |
| 93 | Mike Menosky# | 114 | 1986-1999 | |
| 93 | A J Pierzynski# | 114 | 1986-1999 | |
| 97 | Del Gainer# | 112 | 1993-1999 | |
| 97 | Willie Keeler# | 112 | 1986-1999 | |
| 99 | Dick Hoblitzell | 110 | 1985-1997 | |
| 100 | Bill Skowron# | 107 | 1995-1999 |
